Tokyo, Japan, November 26, 2009 – Pfizer Japan Inc. (“Pfizer”) and Astellas Pharma Inc. (“Astellas”) today announced that combination drug of hypertension treatment and hypercholesterolemia treatment Caduet® Combination Tablets (generic name: amlodipine besylate and atorvastatin calcium) will be launched on December 2, 2009 in Japan.

Caduet Combination Tablets is an oral combination drug of a hypertension treatment Norvasc® Tablets (generic name: amlodipine besylate) sold by Pfizer and a hypercholesterolemia treatment Lipitor® Tablets (generic name: atorvastatin calcium) co-promoted by Pfizer and Astellas. Caduet Combination Tablets is a single tablet to combine the most prescribed drugs for hypertension and hypercholesterolemia to help with both treatments, and it is expected to improve medication adherence. Caduet Combination Tablets is now approved in more than 70 countries/areas, and Pfizer has obtained approval to manufacture and market Caduet Combination Tablets in Japan on July 7, 2009. Pfizer is responsible for manufacturing and sales of Caduet Combination Tablets, and Pfizer and Astellas will co-promote it.

Pfizer and Astellas have established great partnership through co-promotion of Lipitor Tablets. The companies are committed to work hard to maximize the product value of Caduet Combination Tablets and expect to further contribute to hypertension and hypercholesterolemia treatment.