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Astellas believes that maintaining a healthy global environment is an essential theme for building a sustainable society, and it is also an important element in ensuring the continuation of business activities. For Astellas to achieve sustainable growth, we must fulfill our corporate social responsibilities regarding issues that impact the local environment, including climate change problems, environmental pollution, and waste disposal. Astellas strives to develop its aspirations for the company based on a long-term timeframe and global perspective. At the same time, we continue efforts to address regional social issues and pursue corporate activities in harmony with the global environment.
Our Environmental Action Plan sets out short-term and medium-term targets for our activities regarding the key points of the Astellas Environment, Health & Safety Guidelines. We renew our action plans on a rolling basis, by reviewing progress and conditions during the previous year and incorporating our findings into our action plan for the following year.
In November 2018, the Environmental Action Plan involving Climate-Related Measures obtained Science Based Target (SBT) certification from the SBT Initiative, which recommends that private companies set reduction targets aligned with the Paris Agreement, which entered into force in 2016, and Astellas operated under that, but reviewed GHG emission targets towards achieving the targets of 1.5℃ (Scope 1 and 2) and well-below 2℃ (Scope 3). In January 2023, the SBT Initiative approved the targets as a science-based initiative, and Astellas has moved forward on a new environmental Action Plan (Climate Change Mitigation Measures). Our environmental action plans for natural resource conservation and waste management have been effectively managed, and even more ambitious targets have been established starting from fiscal 2021. We are continuously implementing measures eyeing the target fiscal years of each plan. Results for fiscal 2024 are as follows:
Results of Fiscal 2024
Item | Goal | Fiscal 2024 Results | |
---|---|---|---|
Measures to Address Climate Change | Reduce GHG emissions (Scope 1 + Scope 2) by 63% by fiscal 2030 (Base year: fiscal 2015) (Emissions in the base year: 201 kilotons) [1.5°C target] | Ratio to base year 40% decrease | |
(Emissions: 108 kilotons) | |||
Reduce GHG emissions (Scope 3) by 37.5% by fiscal 2030 (Base year: fiscal 2015) [well below 2°C target] | Ratio to base year 7% decrease (Emissions: 1,276 kilotons) | ||
Measures for the Conservation of Natural Resources | Enhance water resource productivity*1 by around 20% of the fiscal 2016 result by the end of fiscal 2025 | Ratio to base year 86% improvement | |
Waste management | Improve waste generated per unit of revenue*2 by around 10% of the fiscal 2016 result by the end of fiscal 2025 | Ratio to base year 45% improvement | |
Biodiversity | Quadruple the biodiversity index by fiscal 2025 from the fiscal 2005 level | Ratio to base year 6.7 times |
Being prepared for emergency situations caused by an accident or natural disaster can help to prevent an environmental catastrophe and minimize damage. Accordingly, we have developed specific measures and procedures for these situations. Moreover, we conduct regular education sessions and training drills, and reconfirm and test the validity of our procedures, communication networks and the division of roles focusing on risks that are recognized as a high priority. In this manner, we continue to work diligently to reduce environmental risk.
In particular, the discharge of harmful substances could lead to the pollution of rivers as well as cause problems at public sewage treatment plants. This in turn could have a grave impact on regional communities. In preparation for accidents and emergency situations, we are systematically implementing measures for the prevention of environmental pollution, including the installation of backup equipment, while working to reduce the risk of pollution. In addition, to avoid accidents and other problems, we are bolstering efforts to optimize the operation and management of wastewater treatment systems, and monitor and measure the quality of water draining out of our plants to confirm compliance with relevant effluent standards.
There was no incident in which Astellas exceeded the upper limit of agreed values specified in a pollution prevention agreement with the local government. Over the past five years, there were two incidents as below. Astellas reported these incidents to the local government and implemented response measures based on its instructions.
There was no environment-related accident over the past five years. Regarding accidental fugitive emission of fluorinated gases, annual emission data (in CO2 equivalent unit) is disclosed on page “Environment Initiatives”. The numbers of environment-related fine payments and complaints are summarized in the table below.
FY2020 | FY2021 | FY2022 | FY2023 | FY2024 | |
---|---|---|---|---|---|
Fine payment | 0 | 0 | 0 | 0 | 1*1 |
Complaints | 0 | 0 | 0 | 1 | 1*2 |
*1It turned out that an outsourced vendor did not test one of parameters on discharged wastewater in one of periodic tests and Astellas paid 145 USD.
*2There was a complaint about the sound of the emergency fire alarm during its periodic test.
Drawing on the results of soil contamination assessments completed over the past five years, there have been no sites where contamination has been found.
Mitigating and adapting to the threat posed by climate change requires active involvement by national governments, local governments, corporations, citizens, and others. Astellas recognizes that climate change will become a constraint on conducting sustained corporate activity and considers it an important management issue to address.
Astellas has made a long-term commitment to taking measures against climate change and decided to aim for achieving a 90% reduction in GHG emissions and a 10% neutralization of residual emissions to achieve Net Zero by 2050, based on 2015, for Scope 1 and 2 and Scope 3, respectively. In addition, the Science Based Targets (SBT) initiative approved Astellas’ GHG emissions reduction targets through 2030.
To address climate change as a management issue, we have adopted as targets, the 1.5℃ (Scope 1 and 2) and well-below 2℃ (Scope 3) targets of the Paris Climate Agreement.
Environmental Action Plan (climate change mitigation measures) (SBT re-certified in January 2023)
Progress on the Action Plan (SBT)
Our results calculated based on the GHG Protocol are as follows:
Progress on Environmental Action Plan(Scope1+2)
Progress on Environmental Action Plan (Scope 3)
FY2015 | FY2022 | FY2023 | FY2024 | |
---|---|---|---|---|
Scope 3 GHG emission(t-CO2e) | 1,378,972 | 893,617 | 1,121,350 | 1,276,323 |
vs fiscal 2015(%) | -- | -35% | -19% | -7% |
Changes in Actual GHG Emissions Volume by Area
(Unit: Tons)
Fiscal 2015 | Ratio (%) | Fiscal 2022 | Ratio (%) | Fiscal 2023 | Ratio (%) | Fiscal 2024 | Ratio (%) | |||
---|---|---|---|---|---|---|---|---|---|---|
Japan | 154,447 | 77 | 89,709 | 78 | 92,325 | 77 | 82,224 | 76 | ||
Scope 1 | 56,674 | 44,253 | 40,601 | 35,558 | ||||||
Scope 2 | 97,774 | 45,456 | 51,724 | 46,666 | ||||||
Outside of Japan | 46,506 | 23 | 25,815 | 22 | 27,846 | 23 | 25,609 | 24 | ||
Scope 1 | 28,082 | 14,798 | 16,523 | 16,654 | ||||||
Scope 2 | 18,424 | 11,017 | 11,323 | 8,955 | ||||||
Global | 200,953 | - | 115,524 | - | 120,171 | - | 107,833 | - | ||
Scope 1 | 84,756 | 59,051 | 57,124 | 52,212 | ||||||
Scope 2 | 116,197 | 56,473 | 63,047 | 55,621 |
Non-energy GHG emissions are less than 5% of total emissions and therefore not included in the disclosed data. See the EHS Report 2025 for detailed data by area.
In order to reduce GHG emissions, Astellas must implement management practices that involve the entire Astellas organization from a medium-term perspective. Astellas’ manufacturing plants, research centers, sales and marketing divisions, and offices are implementing a variety of initiatives with the aim of mitigating climate change.
Regarding tangible elements, efforts to improve facilities, which include the introduction of high-efficiency equipment and the conversion to alternative fuels, are expected to make a significant contribution to reducing the level of GHG emissions generated by energy sources. Regarding intangible aspects, employees’ participation in energy saving through improvements of daily work is also important. To this end, each facility adopts a two-pronged approach, comprising measures related to both tangible and intangible elements.
In fiscal 2024, Astellas completed approximately 2,200 million yen in investments with a focus on the promotion of renewable energy use at each facility (including the installation of solar panels) and energy-saving measures (such as upgrading to air conditioning-related energy-saving equipment and introducing LED lighting), resulting in a reduction of GHG emissions of 2,905 tons.
Astellas will keep on conducting continuous reviews of investment plans related to matters such as renewable energy.
In addition to emissions directly generated by business activities (Scope 1 and Scope 2) in the Environmental Action Plan concerning climate change, Astellas is also striving to assess emissions produced throughout the entire supply chain (Scope 3). We have also set SBTs for GHG emissions from major categories within Scope 3 and are striving to reduce them. In addition, we encourage support and cooperation with our measures to reduce GHG emissions, including transactions among our production contractors. For details on Scope 3 GHG emmisions, please refer to ESG Data
At Astellas’ research and production bases, we use boilers fueled by city gas, LPG and LNG (liquefied natural gas), all of which generate low GHG emissions during combustion. These boilers not only contribute to reducing GHG emissions, but also to reducing SOx emissions, another air pollutant.
Knowing exactly how much energy we use is useful for the formulation of new strategies. We have introduced energy monitoring systems that can visually monitor energy usage at our facilities.
Since fiscal 2008, Astellas has been striving to reduce GHG emissions associated with the use of our sales fleets. In each region, we are continuously switching over to vehicles with low environmental impact (e.g., hybrid cars, electric vehicles). In Japan and the US, where the rate of introducing hybrid vehicles is high, the volume of GHG emissions relative to the number of vehicles has been reduced more than in other regions.
GHG emissions associated with the use of sales fleets are reported under Scope 1 (fuel use) and Scope 2 (electricity use in electric vehicles).
(Unit: Tons)
Fiscal 2015 | Fiscal 2022 | Fiscal 2023 | Fiscal 2024 | |
---|---|---|---|---|
Total emissions from sales fleets | 28,725 | 12,378 | 13,380 | 13,323 |
When it cannot be directly measured, CO2 emissions are estimated based on fuel purchase costs, annual average fuel usage by company vehicles or private vehicles (if used in sales activities) and other factors. Figures do not include data from Asia/Oceania region (with partial exception).
Starting from the 19th term business year (fiscal 2023), Astellas has incorporated a new key performance indicator by setting sustainability performance targets for bonus (short-term incentive remuneration) for Directors who are not the Audit & Supervisory Committee Members (and excluding Outside Directors). By linking management strategies with incentive compensation, Astellas aims to steadily promote environmental initiatives.
For details of remuneration for Directors, please refer to page 74 of the Notice of Convocation of the 19th Term Annual Shareholders Meeting.
The use of renewable energy is one of the most effective climate change countermeasures. Astellas is introducing photovoltaic panels and wind power generation, and equipment such as biomass boilers. Astellas is also purchasing electricity derived from renewable energy sources to reduce GHG emissions. We will continue to strive for expanding the use of renewable energies to help achieve Net Zero.
Fiscal 2015 | Fiscal 2022 | Fiscal 2023 | Fiscal 2024 | |
---|---|---|---|---|
Total energy used (GWh) | 1,091 | 570 | 558 | 495 |
Energy derived from renewable energy sources (GWh) | 58 | 108 | 104 | 93 |
Renewable energy rate (%) | 5 | 19 | 19 | 19 |
Total electricity (GWh) | 279 | 227 | 229 | 208 |
Electricity derived from renewable energy sources (GWh) |
48 | 95 | 91 | 80 |
Renewable energy rate (%) | 17 | 42 | 40 | 39 |
* From the disclosure of fiscal 2022 results, the amount of energy consumed by the use of purchased electricity and electricity generated internally using renewable energy sources (solar power, wind power, etc.) is converted at 3.6 MJ per 1 kWh.
Starting in April 2020, Astellas switched all electricity purchased by its three business sites in Ibaraki Prefecture (Tsukuba business site, Tsukuba Tokodai business site, and Takahagi business site) to an electricity rate plan deemed to be 100% hydroelectric (*). (This enabled a reduction of emissions equivalent to about 26,000 tons of GHG emissions in fiscal 2024.)
Moreover, we are also moving ahead on switching to electricity generated by renewable energy sources in areas outside of Japan. Looking ahead, Astellas will continue to explore opportunities for using renewable energy, and it will also consider formulating targets for the use of renewable energy.
(*) The Aqua Premium plan provided by TEPCO Energy Partner, Inc.
Astellas is participating in the Carbon Neutrality Action Plan* formulated by the Federation of Pharmaceutical Manufacturers’ Associations of Japan, which is based on requests from the Federation of Economic Organizations. In February 2023, Astellas committed to a policy of reducing GHG emissions from operations to Net Zero by 2050.
*With a long-term vision of Net Zero CO2 emissions by 2050, the Phase II target (2030 target) is to reduce CO2 emissions in fiscal 2030 by 46% (from laboratories, plants, offices and vehicles used in sales) from the fiscal 2013 level.
Breakdown of Energy Consumption
Global energy usage in fiscal 2024 by the Astellas Group amounted to 496 GWh, for a decrease of 11% (62 GWh) over the previous year. The percentage of total energy consumption accounted for by electricity is high because in each region a large amount of electricity is consumed by the operation of air conditioning equipment.
Astellas strives to reduce its energy consumption, including through the continued implementation of energy-saving measures and the introduction of highly efficient equipment.
For Breakdown of Energy Consumption, please refer to ESG Data
(Unit: MWh)
Fiscal 2021 |
Ratio (%) |
Fiscal 2022 |
Ratio (%) |
Fiscal 2023 |
Ratio (%) |
Fiscal 2024 |
Ratio (%) |
||
Global | 800,563 | - | 569,850 | - | 558,039 | - | 495,653 | - | |
Electricity Purchased (Renewable energy sourced |
277,366 46,454 |
39 | 225,526 93,048 |
40 | 226,691 88,530 |
41 | 205,352 77,433 ) |
41 | |
Gaseous fuel | 382,356 | 48 | 267,124 | 47 | 252,061 | 45 | 210,279 | 42 | |
Liquid fuel | 120,928 | 10 | 53,894 | 9 | 56,069 | 10 | 56,777 | 11 | |
Heat purchased | 8,005 | 2 | 8,722 | 2 | 8,244 | 1 | 7,790 | 2 | |
Renewable energy | 12,009 | 2 | 14,584 | 3 | 14,974 | 3 | 15,455 | 3 |
(Unit: MWh)
Fiscal 2021 |
Ratio (%) |
Fiscal 2022 |
Ratio (%) |
Fiscal 2023 |
Ratio (%) |
Fiscal 2024 |
Ratio (%) |
||
Japan | 421,691 | - | 407,447 | - | 387,641 | - | 349,301 | - | |
Electricity Purchased (Renewable energy sourced |
167,760 66,993 |
40 | 167,420 64,049 |
41 | 167,043 60,576 |
43 | 160,803 59,281 ) |
46 | |
Gaseous fuel | 241,391 | 57 | 226,994 | 56 | 209,395 | 54 | 177,842 | 51 | |
Liquid fuel | 12,139 | 3 | 12,903 | 3 | 10,969 | 3 | 9,795 | 3 | |
Heat purchased | 349 | 0.1 | 82 | 0.0 | 60 | 0.0 | 4 | 0.0 | |
Renewable energy | 52 | 0.0 | 48 | 0.0 | 174 | 0.0 | 858 | 0.2 |
(Unit: MWh)
Fiscal 2021 |
Ratio (%) |
Fiscal 2022 |
Ratio (%) |
Fiscal 2023 |
Ratio (%) |
Fiscal 2024 |
Ratio (%) |
||
Outside of Japan | 159,741 | - | 162,403 | - | 179,398 | - | 146,352 | - | |
Electricity Purchased (Renewable energy sourced |
56,335 28,889 |
35 | 58,107 28,999 |
36 | 59,648 27,954 |
35 | 44,549 18,153 ) |
30 | |
Gaseous fuel | 36,652 | 23 | 40,130 | 25 | 42,665 | 25 | 32,437 | 22 | |
Liquid fuel | 43,635 | 27 | 40,991 | 25 | 45,100 | 26 | 46,982 | 32 | |
Heat purchased | 10,031 | 6 | 8,639 | 5 | 8,184 | 5 | 7,786 | 5 | |
Renewable energy | 13,088 | 8 | 14,536 | 9 | 14,800 | 9 | 14,597 | 10 |
Sustainable biodiversity initiatives
Astellas is thankful for the benefits brought about by biological diversity and understands all of its business activities have an impact on ecosystems. We will make a positive contribution to the preservation of biodiversity by working to lessen that impact. Furthermore, we actively contribute to the creation of a society that coexists with the natural world, enabling the preservation of biodiversity and the sustainable use healthy ecosystems. Astellas endorses the Declaration of Biodiversity by Keidanren (Japan Business Federation) and makes donations to the Keidanren Nature Conservation Fund.
Astellas assesses three main factors that are causing the deterioration of biodiversity: environmental pollution, resource consumption, and climate change. We have created a Biodiversity Index to evaluate the impact of our business activities on biodiversity.
The environmental burden for each sub-category in the assessment fiscal year is divided by the corresponding burden in the base-year and then multiplied by the weight to derive the “biodiversity burden index.” The “biodiversity index” is calculated by dividing Astellas’ consolidated revenue in the assessment fiscal year by the total of all the biodiversity burden index figures. Improvement can be determined by comparing this index to the base year.
Raise the Biodiversity Index to quadruple the fiscal 2005 level by fiscal 2025. (Global)
The Biodiversity Index for fiscal 2024 came in at 6.7 times the figure recorded in fiscal 2005.
Biodiversity Index
(Unit: MWh)
The Biodiversity Burden Index and Revenue
(Unit: MWh)
Initiatives for resource recycling
Astellas recognizes that since the use of sustainable resources is essential for continuing its business activities, it must play an active role in the creation of a recycling-oriented society. We have established an Environmental Action Plan and are moving forward with steps to effectively use water resources and recycle waste materials (reuse, recycling, and use of all thermal energy) as initiatives contributing to a recycling-oriented society.
Effective Use of Water Resource
The effective use of water resources serves as a useful indicator for gauging society’s impact on biodiversity. Astellas assesses the relationship between water resources and economic activity using a water resource productivity index and has been striving to improve this index. Water resource productivity for fiscal 2023 improved significantly by 65% compared with the base year of fiscal 2016.
For details on Changes in Volume of Water Resources Withdrawn and Revenue, please refer to ESG Data
Recycling of Water and Reducing Water Consumption
Astellas’ operations use only water drawn from service water, industrial water and ground water. Water used in work operations is treated in accordance with wastewater discharging standards and returned to an aquatic environment. In addition, Astellas is continuously working to reduce water consumption while minimizing process wastewater.
Risk Assessments
Water is indispensable for Astellas’ research and production activities. Each business site obtains necessary government approval to use water, and wastewater is discharged after being treated to satisfy wastewater discharging standards.
Moreover, Astellas uses Aqueduct provided by World Resources Institute to analyze water risks specific to the operating regions where its plants and other facilities are located
The Astellas Group on a global basis does not currently withdraw water from water bodies in areas concerned with water resource depletion. As water risks may emerge in the future because of climate change, we are conducting risk analysis and taking steps to minimize our dependence on such resources, and also regard this as an effective means of ensuring business continuity
Waste Management
Astellas is promoting efforts to reduce the waste landfill volume to as close to zero as possible through proactive recycling and reuse of waste materials. Moreover, Astellas also evaluates the relationship between waste generation volume and economic activities with the index known as the Waste generated per unit, and the Company is making efforts to improve it.
In fiscal 2024, the waste generated per unit improved 45% over the base year (fiscal 2016).
For detail on Changes in Waste Generation Volume and Revenue, please refer to ESG Data.
Waste Management in the Value Chain
In waste management, it is also important to prevent environmental pollution being caused by hazardous waste generated by research centers and manufacturing plants and the illegal disposal of that waste. As a means of prevention, we first examine appropriate methods of waste disposal and then conduct regular on-site assessment that waste treatment contractors are using appropriate waste treatment methods.
Handling status of High-Concentrate PCB-contaminated Waste Storage
We have been systematically conducting detoxification of any high-concentrate PCB-contaminated equipment that is stored by Astellas. All PCB waste was treated during fiscal 2023.
Initiatives for Preventing Pollution
Astellas promotes activities to prevent global environmental pollution. For major environmental management indicators for air and water quality, we have set and manage stricter voluntary control values than the values stipulated by laws and regulations and agreed values. In addition, we are promoting voluntary activities to reduce atmospheric emissions of chemical substances.
Reduction of VOC Emissions
Astellas sets voluntary numerical targets for reducing the amount of volatile organic compounds (VOCs) that are emitted accompanying the use of solvents in production and research activities and makes efforts to reduce emissions. Moreover, as a measure to prevent environmental pollution by chemical substances as well as occupational illnesses, we are taking steps to minimize the impact of our business operations on our employees, local communities, and the environment, such as development of new manufacturing processes that do not use highly hazardous chemical substances.
Reduction of NOx Emissions
To reduce the emission of NOx into the atmosphere, Astellas has installed boilers that use gaseous fuels (city gas, LNG, and LPG). The NOx emissions from all business facilities in Japan are as shown in the table below. The NOx emissions from non-Japanese production facilities in fiscal 2024 amounted to 3 tons.
Astellas does not use any equipment that runs on fuel oil, which is a major source of SOx (sulfur oxide) emission.
Changes in Emissions Volume
For detail on Changes in Emissions Volume, please refer to ESG Data
Astellas measures the extent of its impact on aquatic environments using the biochemical oxygen demand (BOD) load as an index in Japan and the chemical oxygen demand (COD) load as an index in other countries and makes the data available to the public. In Japan, the BOD load was 8 tons, a 11% increase from the previous fiscal year. Outside Japan, the COD load was 14 tons.
Since the discharge into water of chemical substances used in manufacturing processes can have a negative impact on ecosystems, we are examining ways of reducing such discharges as much as possible at all stages from R&D onward. With respect to future drug candidate substances discovered and developed by Astellas, we are examining the impact pharmaceuticals would have on ecosystems through the evaluation of their biodegradability in the natural environment.
For detail on Changes in BOD Load and Changes in Drainage Volume, please refer to ESG Data.
Further information on PRTR system
Japan's PRTR Act designates substances that are harmful to human beings and recognized to widely exist in the environment. The main aim of the act is to confirm the nature of the releases and transfers of a company and link the results to independent assessments and improvement of voluntary chemical substance management. The table below shows the release and transfer of PRTR-designated substances that we identified and reported in fiscal 2024. Our total amount of designated chemical substances released into the environment in fiscal 2024 was 1 ton. Astellas has kept low quantity emission since 2019.
PRTR : Refers to chemical substances designated under Japan's Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof (Pollutant Release and Transfer Register Law)
For detail on Release and transfers of PRTR chemical substances in fiscal 2024,please refer to ESG Data
Environmental impact of products and countermeasures
Astellas does not handle or sell any product that uses hydrofluorocarbons (HFCs) as a filler agent.
The products manufactured and marketed by the Company are administered to patients through medical institutions. After their use, packaging materials are disposed of by hospitals, pharmacies, and general households. The waste discarded by general households is mainly comprised of blister (plastic) packaging used for tablets and capsules. Hospitals and pharmacies discard blister packaging as well as various types of plastics including bottles and tubes, metals, glass materials used in injectable solutions products, and paper items such as individual packaging and cardboard boxes.
In the case of pharmaceutical packaging, certain functions remain essential to ensure the safe storage of products as well as compliance with the provisions stipulated under the Pharmaceutical and Medical Device Act of Japan and the laws and regulations of respective countries. In addition to these functions and requirements, Astellas selects environmentally friendly materials for use in its packaging while engaging in a variety of initiatives including the labeling of materials to promote recycling at the time of disposal.
One initiative is to start using blister sheet biomass plastic made from plant-derived raw material. Blister packaging is eco-friendly packaging using 50% of raw materials from sugarcane-derived polyethylene, a biomass plastic. Blister packaging is required to have a high level of tablet protection and usability, and by using a packaging technology developed over many years, it meets these requirements and can be mass-produced. In fiscal 2021 Astellas started using blister packaging made from plant-derived raw materials for some products in Japan.
To encourage the recycling of containers and packaging for household use in Japan, in accordance with the Containers and Packaging Recycling Law sellers of products are responsible for defraying the costs of recycling such waste products. The estimated total amount of plastic and paper containers and packaging used in Astellas products in fiscal 2024 is 107 tons, and the Company was requested to pay ¥4.20 million in recycling costs.
Astellas uses plastics in various products and recognizes that handling plastic waste generated in its business activities is an environmental issue. We endeavor to recycle plastic resources. In Japan, a law was enforced in April 2022 to promote the recycling of resources related to plastic. The amount of plastic waste generated in Japan in fiscal 2024 was 244 tons. Astellas is working to limit the amount of plastic waste it generates within Japan to under 250 tons by limiting the use of plastic resources and improving recycling rates.
Governance
Astellas is committed to improving the health of people around the world through the provision of innovative and reliable pharmaceutical products to sustainably enhance enterprise value by being chosen and trusted by all stakeholders. Please see details about Astellas’ governance initiatives in the following: