Astellas considers contributing to the sustainability of society through its business activities to be a key management priority. In addressing climate change, we are advancing initiatives aligned with the goals of the Paris Agreement. In 2023, we established a target to reduce greenhouse gas (GHG) emissions from Scope 1 and Scope 2 by 2030 and announced our ambition to achieve net-zero emissions by 2050.

In FY2025, we made steady progress toward these goals. This included the installation and expansion of on-site solar power generation at our Dublin and Shenyang plants, as well as the commencement of off-site renewable electricity procurement through corporate power purchase agreements (PPAs) at our Yaizu and Toyama facilities. As a result of these efforts, reductions in Scope 1 and Scope 2 emissions are progressing in line with our 2030 target trajectory.

At the same time, we recognize that reducing Scope 3 emissions across our value chain remains a significant challenge. In FY2025, we advanced initiatives to incorporate emissions data directly provided by our business partners (primary data) into our Scope 3 emissions calculations. In parallel, we joined the Energize program, a global initiative aimed at accelerating the adoption of renewable energy among suppliers and other business partners.

With respect to biodiversity, in FY2025, our biotope conservation plan at the Yaizu site and our green space conservation plan at the Tsukuba site were certified as “Other Effective Area-based Conservation Measures” (OECMs) under Japan’s Act on Promotion of Regional Biodiversity. These initiatives are aligned with the “Kunming–Montreal Global Biodiversity Framework,” adopted at COP15, including its 30by30 target to conserve 30% of the world’s land and sea areas by 2030.

In addition, beginning this year, we have transitioned from publishing a standalone EHS Report in PDF format to issuing an integrated ESG Report that provides a more comprehensive overview of our sustainability initiatives and performance. Astellas will continue to enhance the transparency, consistency, and credibility of its sustainability disclosures, while responding to evolving international standards and stakeholder expectations.