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This lab works to gain new insights into the tumor microenvironment for cancer drug discovery. It will leverage the Kashiwa-no-ha area, where leading Japanese cutting-edge medical facilities and academic institutions, including the National Cancer Center Japan, are located.
Facilities
Lab equipment
Cutting-edge spatial information analyzers and machine learning technologies including:
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CosMx™ Spatial Molecular Imager (SMI) is high-plex in situ analysis platform to provide spatial multiomics with FFPE and fresh frozen tissue samples at a single cellular and subcellular resolution. CosMx™ enables rapid quantification and visualization of up to 1,000 RNA and 64 validated protein analytes, and in January 2024 New 6K Discovery panel will enable analysis of entire Reactome at the single cell level.
Xenium builds on years of innovation in single cell and spatial technologies of 10x genomics to deliver the most advanced end-to-end high-plex in situ platform on the market. The purpose-built design streamlines going from tissue section to data, with an automated analyzer, curated and/or custom panels, and intuitive visualization and analysis software. Xenium enables high-throughput subcellular mapping of 100s to 1,000s of RNA targets in addition to multiplexed protein on a tissue section.
Orion is a benchtop, high resolution, whole slide multimodal imaging instrument enabling robust spatial biology studies and biomarker quantitation using a combination of quantitative immunofluorescence and bright field imaging. Utilizing a swift sample-to-data workflow, all channels are acquired across the entire slide, in one scan, while rapid data processing enables whole slide, unbiased quantitation. By combining speed and resolution, Orion enables comprehensive phenotypic profiling and characterization of tissue architecture, tumor heterogeneity, and the immune response for whole sections in hours, not days.
Real-Time PCR System, All-in-One Fluorescence Microscope, Multi-mode plate reader, NanoDrop, etc.
Please check here to learn more about MITSUI LINK-Lab KASHIWA-NO-HA 1 users’ shared lab equipment.
Address:
6-6-2 Kashiwa-no-ha, Kashiwa City, Chiba
Access:
3 minutes by bus from “Kashiwanoha-campus” Station on the Tsukuba Express line,
3 minutes on foot from “Mitsui Garden Hotel Kashiwa-no-ha Park Side Mae (Zeikan Kenshujo)” bus stop
