ESG data

Environment

The performance indicators marked with check_boxand check_boxhave been independently assured by EY ShinNihon LLC. For details, please refer to the Independent Assurance Report.

check_box Independent Assurance Report (Jun 13^th 2025)

check_box Independent Assurance Report (Aug 8^th 2025)

Reporting coverage, methods, etc. (Aug 8^th 2025)

Direct interaction between Astellas and the Environment (Results for Fiscal 2024)

Direct Interaction

INPUT		OUTPUT
Energy ^*1		GHGs^{1 4}
Purchased electricity	205,273 MWh check_box Renewable derived 77,628 MWh check_box	Scope 1	52,212 t-CO₂ check_box
		Scope 2	55,621 t-CO₂check_box
		Pollutants (atmosohere)^*5
Gaseous fuel	210,279 MWh check_box	NOx	16 tons check_box
Gaseous fuel	210,279 MWh check_box	VOC	22 tons check_box
Liquid fuel	55,942 MWh check_box	Water discharge, pollutants (water body)
Purchased heat	7,790 MWh check_box	Water discharge^*2	6,690 thousand m³ check_box
Other renewable energy	15,455 MWh check_box	BOD^*5	8 tons check_box
Resource		COD^*5	20 tons
Water ^*2	6,883 thousand m³ check_box	Waste material
Raw materials and consumables (by weight)^*3	4,457 tons check_box	Volume of waste generated^*6	11,447 tons check_box
Raw materials and consumables (by weight)^*3	4,457 tons check_box	Landfill volume^*5	22 tons check_box

^*1All Astellas business facilities

^*2All production sites and R&D sites. (The volume of water discharge from non-Japanese sites was equivalent to that of withdrawal.)

^*3Items used at commercial production sites in Japan that can be ascertained on a weight or volume basis. Consumable supplies are those used in commercial production process.

^*4Non-energy-related GHG emissions are not included. The CO2 equivalent of fluorinated gases from production sites (global) and R&D sites (Japan) was 1,724 tons- CO2.

^*5Japanese production sites and R&D sites

^*6All Japanese facilities, and all production and R&D sites outside of Japan

Indirect GHGs (Scope 3)

（Unit：t-CO2e）

Upstream Scope 3 emissions		Downstream Scope 3 emissions
1. Purchased goods and services	1,082,536	9. Transportation and distribution (downstream)	15,048
2. Capital goods	90,582	10. Processing of sold products	Not relevant
3. Fuel and energy related activities (not included in Scope 1 and Scope 2)	27,410	11. Use of sold products	Not applicable
4. Transportation and distribution (upstream)	19,987	12. End-of-life treatment of sold products	246
5. Waste generated in operation	1,151	13. Downstream leased assets	3,301
6. Business travel (by airplane)	34,056	14. Franchises	Not relevant
7. Employee commuting	2,004	15. Investments	Not relevant
8. Upstream leased assets	Not relevant

INPUT

Breakdown of Energy Consumption

(Unit: MWh)

	Fiscal 2021	Ratio^*1 (%)	Fiscal 2022	Ratio^*1 (%)	Fiscal 2023	Ratio^*1 (%)	Fiscal 2024	Ratio^*1 (%)
Global	581,432		569,850		558,039		494,739 check_box
(Renewable Sourced (renewable energy ratio	109,022 19%		107,633 19%		103,504 19%		93,083check_box 19%check_box
Total electricity consumption^*2 (Renewable Sourced (renewable energy ratio)	225,744 97,531 43%		227,486 95,008 42%		228,688 90,527 40%		207,703 check_box 80,059check_box 39% check_box
by energy source
Electricity Purchased (Renewable Sourced	224,095 95,882		225,526 93,048		226,691 88,530		205,273 check_box 77,628 check_box
Gaseous fuel	278,044		267,124		252,061		210,279 check_box
Liquid fuel	55,775		53,894		56,069		55,942 check_box
Purchased heat	10,379		8,722		8,244		7,790 check_box
Renewable energy （self-generated electricity	13,140 1,650		14,584 1,960		14,974 1,997		15,455 check_box 2,431 check_box
Japan	421,691	73	407,447	72	387,641	69	349,301 check_box	70
by energy source
Electricity Purchased (Renewable Sourced	167,760 66,993		167,420 64,049		167,043 60,576		160,803 check_box 59,476 check_box
Gaseous fuel	241,391		226,994		209,395		177,842 check_box
Liquid fuel	12,139		12,903		10,969		9,795 check_box
Purchased heat	349		82		60		4 check_box
Renewable energy	52		48		174		858 check_box
Overseas	159,741	27	162,403	28	179,398	31	145,438 check_box	30
by energy source
Electricity Purchased (Renewable Sourced	56,335 28,889		58,107 28,999		59,648 27,954		44,470 check_box 18,153 check_box
Gaseous fuel	36,652		40,130		42,665		32,437 check_box
Liquid fuel	43,635		40,991		45,100		46,147 check_box
Purchased heat	10,031		8,639		8,184		7,786 check_box
Renewable energy	13,088		14,536		14,800		14,597 check_box

*¹ The proportion of energy consumption in Japan and overseas relative to the global total.
*² The amount of purchased electricity and self-generated electricity from renewable sources.

Changes in Volume of Water Resources Withdrawn and Revenue

		Fiscal 2016	Fiscal 2022	Fiscal 2023	Fiscal 2024
Volume of water resource withdrawn (thousand m³)		8,774	6,864	6,497	6,883check_box
	Service water and industrial water	8,017	6,430	6,151	6,484check_box
	Groundwater	758	434	346	399check_box
Japan	Service water and industrial water	7,705	6,231	5,952	6,286
	Groundwater	758	434	346	399
US	Service water and industrial water	146	55	61	68
	Groundwater	-	-	-	-
Established Markets	Service water and industrial water	145	129	124	111
	Groundwater	-	-	-	-
Greater China	Service water and industrial water	21	15	14	18
	Groundwater	-	-	-	-
International Markets	Service water and industrial water	-	-	-	-
	Groundwater	-	-	-	-
Revenue (billions of yen)		1,312	1,519	1,604	1,912
Water resource productivity (billions of yen／thousand m³)		0.15	0.22	0.25	0.28check_box
Improvement from Base-year		-	48%	65%	86%check_box

No water was withdrawn from a source other than service water, industrial water, or groundwater

Target: Production facilities and R&D sites in Japan and overseas

OUTPUT

Changes in Actual GHG Emissions Volume

（Unit：t-CO₂）

		Fiscal 2015	Ratio (%)	Fiscal 2022	Ratio (%)	Fiscal 2023	Ratio (%)	Fiscal 2024	Ratio (%)
Japan		154,447	77	89,709	78	92,325	77	82,224check_box	76
	Scope 1	56,674		44,253		40,601		35,558 check_box
	Scope 2	56,674		45,456		92,325		46,666 check_box
Overseas		46,506	23	25,815	22	27,846	23	25,609check_box	24
	Scope 1	28,082		14,798		16,523		16,654check_box
	Scope 2	18,424		11,017		11,323		8,955check_box
Global		200,953		115,524		120,171		107,833check_box
% change from base year		-		-43%		-40%		-46%check_box
	Scope 1	84,756		59,051		57,124		52,212check_box
	Scope 2	116,197		56,473		56,473		55,621check_box

Please refer to the EHS Report 2025 for detailed data by area.

GHG emissions Volume by Activity

（Unit：t-CO₂）

	FY2015	FY2022	FY2023	FY2024
Emissions from production sites and R&D sites	154,706	96,957	100,860	90,743 check_box
Emissions from office	17,522	6,188	5,932	3,768 check_box
Emissions from company vehicle use	28,725	12,378	13,380	13,323 check_box

GHG data（Scope 3 and Scope 1+2+3）

	FY2015	FY2022	FY2023	FY2024
Scope 3 GHG emission (t-CO₂e)	1,378,972	893,617	1,121,350	1,276,323 check_box
vs fiscal 2015 (％)	--	-35%	-19%	-7%
Scope 1+2+3 GHG emission (t-CO₂e)	1,579,925	1,009,141	1,241,521	1,384,156 check_box
vs fiscal 2015（％)	--	-50%	-21%	-12%
Scope 1+2+3 GHG emission per sales revenue（t-CO₂e/billion JPY)	1,151	665	774	724
vs fiscal 2015 (％)	--	-42%	-33%	-37%

Indirect GHGs (Scope 3)

(Unit：t-CO₂e)

Category	FY2015	FY2022	FY2023	FY2024
Upstream Scope 3 emissions
1. Purchased goods and services ^*1	1,099,263	650,001	857,945	1,082,536
2. Capital goods ^*2	144,053	171,163	178,421	90,582
3. Fuel and energy related activities (not included in Scope1 and Scope2)	28,400	30,096	29,755	27,410
4. Transportation and distribution (upstream) ^*3	17,837	14,942	14,946	19,987
5. Waste generated in operation	3,600	1,281	1,296	1,151
6. Business travel (by airplane)	53,528	6,940	21,496	34,056
7. Employee commuting	5,092	2,119	2,310	2,004
8. Upstream leased assets	Not relevant	Not relevant	Not relevant	Not relevant
Downstream Scope 3 emissions
9. Transportation and distribution (downstream)	26,392	16,602	14,668	15,048
10. Processing of sold products	Not relevant	Not relevant	Not relevant	Not relevant
11. Use of sold products	Not applicable	Not applicable	Not applicable	Not applicable
Upstream Scope 3 emissions
12. End-of-life treatment of sold products	807	424	242	246
13. Downstream leased assets	Not relevant	48	271	3,301
14. Franchises	Not relevant	Not relevant	Not relevant	Not relevant
15. Investments	Not relevant	Not relevant	Not relevant	Not relevant

Discharges into water bodies

Changes in BOD Load

(Unit：tons)

Destination	FY2020	FY2021	FY2022	FY2023	FY2024
BOD	9	9	9	7	8 check_box
Discharge into river	8	8	6	5	7 check_box
Discharge into sewerage system	1	1	3	2	1 check_box

Target: Production sites and R&D sites in Japan

Changes in Water Discharge Volume

（Unit：thousand ㎥）

Destination	FY2020	FY2021	FY2022	FY2023	FY2024
Discharge Volume	7,038	6,810	6,298	6,019	6,492 check_box
Discharge into river	6,835	6,610	6,108	5,834	6,323 check_box
Discharge into sewerage system	203	200	190	185	169 check_box

Scope: Production sites and R&D sites in Japan

Changes in Waste Generation Volume and Revenue

	Fiscal 2016	Fiscal 2022	Fiscal 2023	Fiscal 2024
Waste generation volume (Tons)	14,266	13,541	13,010	11,421 check_box
Japan	11,726	9,787	9,354	8,736
US	54	780	921	720
Established Markets	2,432	2,866	2,655	1,860
China	54	109	81	104
International Markets	-	-	-	-
Revenue(billions of yen)	1,312	1,519	1,604	1,912
Waste generated per unit (Tons/billions of yen)	10.9	8.9	8.1	6.0check_box
Improvement from Base-year	-	18%	25%	45% check_box

Target: Production facilities and R&D sites in Japan and overseas (Note: The amount of Waste generation volume as indicated in Direct interaction between Astellas and the Environment (Results for Fiscal 2024) includes the amount of waste generation volume at our head office.)
*The indicators subject to independent assurance are the waste generation volume and waste generated per unit.

Air Pollution

(Unit：tons)

Substance	Fiscal 2020	Fiscal 2021	Fiscal 2022	Fiscal 2023	Fiscal 2024
NOx	21	17	18	15	16 check_box
VOC	22	21	23	22	22 check_box

Scope: Production sites and R&D sites in Japan.
There are no use of heavy oil fueled equipments and no facilities that are subject to calculations for SOx (sulfur oxide) emissions.

For more details, please refer to the page Environment.

Release and transfer of PRTR Chemical Substances in fiscal 2024

(Unit：tons)

Substance name	Volume handled	Volume released			Volume transferred
Substance name	Volume handled	Air	Water	Soil	Waste	Sewerage
Chloroform	11.437 check_box	0.572 check_box	0.000 check_box	0.000 check_box	10.865 check_box	0.000 check_box
N, N-Dimethylformamide	6.112 check_box	0.007 check_box	0.001 check_box	0.000 check_box	6.034 check_box	0.000 check_box
Hexane	1,893 check_box	0.095 check_box	0.000 check_box	0.000 check_box	1,798 check_box	0.000 check_box
Heptane	16.794 check_box	0.176 check_box	0.001 check_box	0.000 check_box	16.618 check_box	0.000 check_box
Tetrahydrofuran	1.434 check_box	0.008 check_box	0.000 check_box	0.000 check_box	1.309 check_box	0.000 check_box
Toluene	1.207 check_box	0.006 check_box	0.000 check_box	0.000 check_box	1.202 check_box	0.000 check_box

Tabulated based on the target substance list as indicated in the Order for the Enforcement of the PRTR Act, which came into effect on April 1, 2023.
Scope: Production sites and R&D sites in Japan.

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ESG data

Environment