News Release

Yamanouchi Pharmaceutical Co., Ltd.

Announcement Regarding the New Appointment of the Representative Director

September 28, 2004

Tokyo - September 28, 2004 - Yamanouchi Pharmaceutical Co., Ltd.("the Company") hereby announced that at the meeting of the Board of Director held on September 27, 2004, the new appointment of the representative director were determined as follows;

Reason of appointment

To achieve the further enhancement of the business platform
New Position Current Position
Dr.Toshinari Tamura    Representative Director/ Director of the Board/
Corporate Executive Vice President Corporate Executive Vice President

Personal Background

Name: Dr. Toshinari Tamura
Date of Birth: November 30, 1943

Professional Experiences:
   2004 June - present   Director of the Board, Corporate Executive Vice President    2002 - 2004 June     Senior Managing Director
   2001 - 2002 June     Managing Director of the Board
   1998 - 2001 June     Director of the Board
   1997 - 1998             Director of Institute for Drug Discovery Research
   1972                         Joined the Company

Effective Date of Appointment
October 1, 2004